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In mice bred to be deficient in mast cells (kit mutation), fibrosis and a-fib did not develop.[ref] Related article : Atrial fibrillation genes Mast cells are also implicated in the narrowing of the arteries due to atherosclerosis and play a role in stress-induced coronary artery disease

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Although there were only marginal increases in intracellular GSSG levels ( P = 0.064), IL-13 increased extracellular (apical supernatant) GSSG ( P = 0.009), while lowering both GSH ( P = 0.012) and GSH:GSSG ( P = 0.006

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